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Neocutis Exclusive Swiss Technology For The Skin

Neocutis S.A. was founded in February 2003 as a spin-off from the Medical School of the University Hospital of Lausanne, Switzerland. It is a privately held specialty bio-pharmaceutical company focused on wound healing, dermatology and skin care.

Through years of research, physicians discovered fetal skin has a unique ability to heal wounds without scarring. Inspired by this, medical researchers at the University Hospital of Lausanne, Switzerland created a biotechnology process to extract the rich proteins responsible for scarless wound healing from cultured fetal skin cells.

A dedicated cell bank was established for developing new skin treatments using a single biopsy of fetal skin. Originally established for wound healing and burn treatments, today this same cell bank also provides a lasting supply of cells for producing the Neocutis proprietary skin care ingredient Processed Skin Cell Proteins (PSP®).

PSP® - A New Skin Nutrient & Proprietary Product Line

Our skin is in permanent need for bio-restoration. Skin, one of our largest and most visible organs, establishes, controls and transmits contacts with the external world. Beyond the classical image of the skin as a barrier organ and providing physical resistance to mechanical stress, it operates as a huge and highly active biofactory in the synthesis, processing and metabolism of skin constituents including structural proteins, polysaccharides, lipids and a diversity of signaling molecules.

Recent studies suggest that aged or photoaged skin has the same needs as wounded skin, where growth factors and other cytokines interact synergistically to initiate and coordinate the wound healing response. Neocutis Bio-restorative Skin Cream, Journée Bio-restorative Day Cream, Lumière Bio-restorative Eye Cream and Bio-Gel Bio-restorative Hydrogel are the only products to contain PSP®. PSP® provides the most complete and balanced combination of human growth factors and cytokines currently available.


Aging Of The Skin

Human skin, like all other organs, undergoes chronological aging. In addition, unlike most other organs, skin is in direct contact with the environment and therefore ages as a consequence of environmental damage. The primary environmental factor that causes human skin aging is ultraviolet irradiation from the sun. This sun-induced skin aging (called photoaging), like chronological aging, is a cumulative process. Aged and photo-aged skin manifests in fine and deep wrinkles, loss of elasticity, loss of translucency as well as in color and pigmentation changes.

During the last decade, substantial progress has been made in understanding cellular and molecular mechanisms that bring about chronological aging and photoaging. This emerging information reveals that chronological aging and photoaging share fundamental molecular pathways. Aged or photoaged skin show a decreased metabolic activity, decreased cutaneous immune responsiveness including a reduced cytokine production, delayed recovery of barrier function after damage and a reduced wound healing response due to decreased keratinocyte and fibroblast growth capacity. For instance, the time required to reconstitute a competent skin barrier after damage is twice that in the elderly compared to young adults.

On a molecular level, aged skin is characterized by the presence of abnormal, fragmented collagen fibers and diminished total collagen content. Solar ultraviolet irradiation is known to reduce the production of new collagen and causes the breakdown of collagen in the extracellular matrix.

For free consultations and to learn more about the Neocutis product line we offer please contact our Cosmetic Division at (704) 796-1828, and you can also go to the Pixel Perfect, Pain-Free, Hair-Free, Accent Your Body, or Laser360 page of your choice within this website for more information on the laser treatments we offer. Thank you for your interest in Dr. Girouard's Weight Loss & Wellness Clinic.

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LUMIÈRE Bio-restorative Eye Cream

Neocutis before and after Lumiere

Intensive line smoothing eye cream with PSP® helps improve signs of skin aging in the delicate eye area. Formulated with 30% more PSP®, a complete protein blend of Human Growth Factors, Cytokines and Interleukins available to smooth and soften the appearance of fine lines and wrinkles. Experience the following benefits of using this Neocutis eye cream:

  • Helps minimize signs of fatigue
  • Helps alleviate signs of skin puffiness
  • Smooths and refreshes the delicate eye area
  • Smooths the appearance of fine lines and wrinkles
  • Helps reduce the appearance of under eye darkness

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Frequently Asked Questions


What makes Bio-restorative Skin Cream unique?
Bio-restorative Skin Cream is the first cream containing PSP®, which is a balanced mixture of cytokines and growth factors associated with optimal nutritive properties for skin.
Why is PSP® better than a single growth factor?
Years of research on scarless wound healing demonstrated that the interaction of many cytokines, growth factors and their regulators are required for optimal nutrition and bio-restoration of skin.
How is PSP® obtained?
PSP® is obtained from cultured skin cells after cell disruption by several freeze-thawing cycles. The cells are derived from skin cells stored in a cell bank. The PSP® production process is based on standard cell culture technique.
Is PSP® safe for topical use?
PSP® is well tolerated for topical use. It is neither a contact irritant nor a contact allergen. The cells used to initiate PSP® production were free of viruses or viral adventitious agents, mycoplasma, bacteria or fungi. PSP® is produced under stringent manufacturing procedures similarly than required for a biological drug product by regulatory authorities around the world.
Is Bio-restorative Skin Cream well tolerated on sensitive or stressed skin?
The cream was designed for ensuring excellent skin acceptability: free of fragrances, color additives and sunscreens. The good skin tolerability of the cream was confirmed during dermatotoxicology studies. The cream is neither an skin irritant nor a contact allergen.
Can Bio-restorative Skin Cream be used for treating wounds?
Bio-restorative Skin Cream is for external use only and not for application over open or punctured wounds, infections or lacerations.
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